Breaking News

Poxel Sells Kidney‑Disease Drug Candidate to Scynexis for Up to $196 Million

PXL-770 is a novel, highly selective, direct AMPK activator developed for the treatment of autosomal dominant polycystic kidney disease (ADPKD).

Author Image

By: Charlie Sternberg

Associate Editor

Poxel SA, a clinical-stage biopharmaceutical company, has agreed to sell its experimental kidney‑disease drug PXL770 to Scynexis Inc. in a deal worth up to $196 million. The transaction includes an $8 million upfront payment, with as much as $188 million tied to development and commercial milestones. PXL770 (set to be renamed SCY‑770) is a first‑in‑class activator of AMPK, a mechanism aimed at slowing cyst growth in autosomal dominant polycystic kidney disease (ADPKD), the leading genetic cau...

Continue reading this story and get 24/7 access to Contract Pharma for FREE


Already a subscriber? Sign in

Keep Up With Our Content. Subscribe To Contract Pharma Newsletters